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Reproductive outcomes following recurrent first trimester miscarriage: A retrospective cohort study

This retrospective cohort study of 748 women with recurrent miscarriage showed that maternal characteristics such as age, smoking and parental karyotype are associated with subsequent reproductive outcomes. 77% of women conceived and the livebirth rate was 63%.

Authors
Laura Linehan, Indra San Lázaro Campillo, Marita Hennessy, Caragh Flannery, Keelin O'Donoghue
Year
2022
Journal Name
Human Reproduction Open
Category
Journal Article
Keywords
Recurrent miscarriage
Full Citation
Linehan LA, San Lazaro Campillo I, Hennessy M, Flannery C, O’Donoghue K. Reproductive outcomes following recurrent first trimester miscarriage: A retrospective cohort study. Human Reproduction Open. 2022;hoac045. https://doi.org/10.1093/hropen/hoac045.
Link to Publication

Abstract

We studied women who had experienced three miscarriages to see if they had a livebirth, another pregnancy loss or no further pregnancies. We investigated whether features such as medical history, investigations and treatments for recurrent miscarriage were linked to their pregnancy outcome. We found that 77% of women conceived; of these 63% had a livebirth and 36% had a further pregnancy loss. Maternal age, smoking and parental genetic conditions were linked to whether or not a woman conceived and had a baby.

Pregnancy Loss Research Group

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Pregnancy Loss Research Group, Department of Obstetrics & Gynaecology, ÉîÒ¹ÑÇÖÞ¸£Àû¾Ã¾Ã College Cork, Fifth Floor, Cork ÉîÒ¹ÑÇÖÞ¸£Àû¾Ã¾Ã Maternity Hospital, Wilton, Cork, T12 YE02, Ireland,

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